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Schizophrenia Research Forum: Researcher Profile - Javier Costas
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Researcher Profile - Javier Costas

First Name:Javier
Last Name:Costas
Affiliation:Servizo Galego de Saude (SERGAS)
Department:Instituto de Investigacion Sanitaria de Santiago (IDIS)
City:Santiago de Compostela
Email Address:
(view policy) 
Member reports no financial or other potential conflicts of interest. [Last Modified: 16 December 2014]
View all comments by Javier Costas
Clinical Interests:
Drug abuse, Autism spectrum disorders (pervasive developmental disorders), Depression, Schizophrenia, Anxiety disorders , Neurodevelopmental disorders (e.g., 22q11 deletion syndromes)
Research Focus:
Genetics, Bioinformatics/Statistics
Work Sector(s):
Medical hospital, Research institute
Web Sites:
Top Papers
Carrera N, Arrojo M, Sanjuán J, Ramos-Ríos R, Paz E, Suárez-Rama JJ, Páramo M, Agra S, Brenlla J, Martínez S, Rivero O, Collier DA, Palotie A, Cichon S, Nöthen MM, Rietschel M, Rujescu D, Stefansson H, Steinberg S, Sigurdsson E, Clair DS, Tosato S, Werge T, Stefansson K, González JC, Valero J, Gutiérrez-Zotes A, Labad A, Martorell L, Vilella E, Carracedo A, Costas J. Association study of nonsynonymous single nucleotide polymorphisms in schizophrenia. Biol Psychiatry. 2012 Jan 15; 71 (2) :169-77. PubMed PMID:22078303.

Steinberg et al. Common variants at VRK2 and TCF4 conferring risk of schizophrenia. Hum Mol Genet. 2011 Oct 15; 20 (20) :4076-81. PubMed PMID:21791550.

Costas J, Sanjuán J, Ramos-Ríos R, Paz E, Agra S, Tolosa A, Páramo M, Brenlla J, Arrojo M. Interaction between COMT haplotypes and cannabis in schizophrenia: a case-only study in two samples from Spain. Schizophr Res. 2011 Apr; 127 (1-3) :22-7. PubMed PMID:21310591.

Costas J, Sanjuán J, Ramos-Ríos R, Paz E, Agra S, Ivorra JL, Páramo M, Brenlla J, Arrojo M. Heterozygosity at catechol-O-methyltransferase Val158Met and schizophrenia: new data and meta-analysis. J Psychiatr Res. 2011 Jan; 45 (1) :7-14. PubMed PMID:20488458.

Carrera N, Arrojo M, Paz E, Ramos-Ríos R, Agra S, Páramo M, Brenlla J, Costas J. Testing the antagonistic pleiotropy model of schizophrenia susceptibility by analysis of DAOA, PPP1R1B, and APOL1 genes. Psychiatry Res. 2010 Sep 30; 179 (2) :126-9. PubMed PMID:20483474.

Costas J, Gratacòs M, Escaramís G, Martín-Santos R, de Diego Y, Baca-García E, Canellas F, Estivill X, Guillamat R, Guitart M, Gutiérrez-Zotes A, García-Esteve L, Mayoral F, Moltó MD, Phillips C, Roca M, Carracedo A, Vilella E, Sanjuán J. Association study of 44 candidate genes with depressive and anxiety symptoms in post-partum women. J Psychiatr Res. 2010 Aug; 44 (11) :717-24. PubMed PMID:20092830.

Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A, Psychiatric Genetics Network Group. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. Am J Med Genet B Neuropsychiatr Genet. 2009 Sep 5; 150B (6) :808-16. PubMed PMID:19086053.

Stefansson et al. Common variants conferring risk of schizophrenia. Nature. 2009 Aug 6; 460 (7256) :744-7. PubMed PMID:19571808; PubMed Central PMCID: PMC3077530.

Carrera N, Sanjuán J, Moltó MD, Carracedo A, Costas J. Recent adaptive selection at MAOB and ancestral susceptibility to schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2009 Apr 5; 150B (3) :369-74. PubMed PMID:18553363.

Costas J, Carrera N, Domínguez E, Vilella E, Martorell L, Valero J, Gutiérrez-Zotes A, Labad A, Carracedo A. A common haplotype of DRD3 affected by recent positive selection is associated with protection from schizophrenia. Hum Genet. 2009 Jan; 124 (6) :607-13. PubMed PMID:18987889.

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