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Schizophrenia Research Forum: Researcher Profile - Todd Lencz
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Researcher Profile - Todd Lencz

First Name:Todd
Last Name:Lencz
Title:Associate Director of Research
Advanced Degrees:Ph.D.
Affiliation:The Zucker Hillside Hospital
Department:Dept. of Psychiatry Research
Street Address 1:75-59 263rd Street
City:Glen Oaks
Zip/Postal Code:11004
Email Address:
(view policy) 
Member reports no financial or other potential conflicts of interest. [Last Modified: 26 March 2009]
View all comments by Todd Lencz
Clinical Interests:
Research Focus:
Brain imaging, Clinical trials, Genetics, Bioinformatics/Statistics, Neurodevelopment, Phenomenology/diagnosis, Pharamacology
Work Sector(s):
Medical hospital, Research institute
Web Sites:
Reasearcher Bio
Todd Lencz, Ph.D., is Associate Director of Research at the Zucker Hillside Hospital (ZHH), Associate Professor of Psychiatry and Behavioral Science at the Albert Einstein College of Medicine and Associate Investigator at the Feinstein Institute for Medical Research of the North Shore - Long Island Jewish Health System. Dr. Lencz received his B.A. in Psychology from Yale University and Ph.D. in Clinical Psychology from the University of Southern California; he is the author or co-author of more than 70 peer-reviewed scientific publications, focusing on the use of biomarkers, especially novel genetic tools, to refine our understanding of diagnosis, pathophysiology, and course of schizophrenia. Dr. Lencz was amongst the first recipients of the EUREKA award from the National Institute of Mental Health, and has previously received a Career Development Award from NIMH and a Young Investigator Award from NARSAD.
Top Papers
1. Lencz T, Lipsky RH, DeRosse P, Burdick KE, Kane JM, Malhotra AK. (2009). Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypes. British Journal of Psychiatry, 194(4), 313-318.

2. DeRosse P, Lencz T, Burdick KE, Kane JM, Malhotra AK. (2008) The genetics of symptom-based phenotypes: Towards a molecular classification of schizophrenia. Schizophrenia Bulletin, 34(6), 1047-1053.

3.Lencz T, Lambert C, DeRosse P, Burdick KE, Morgan TV, Kane JM, Kucherlapati R, Malhotra AK. (2007) Runs of homozygosity reveal highly penetrant recessive susceptibility loci in schizophrenia. Proceedings of the National Academy of Sciences USA, 104(50), 19942-47. E-pub: 2007 Dec 05. PMID: 18077426

4.Lencz T, Morgan TV, Athanasiou M, Dain B, Reed CR, Kane JM, Kucherlapati R, Malhotra AK. (2007) Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia. Molecular Psychiatry, 12(6), 502-509. Epub: 03/20/07. PMID: 17522711

5. Cornblatt BA, Lencz T, Smith CW, Olsen R, Auther AM, Nakayama E, Lesser ML, Tai JY, Shah MR, Foley CA, Kane JM, Correll CU. (2007) Can antidepressants be used to treat the schizophrenia prodrome? Results of a prospective, naturalistic treatment study of adolescents. J Clin Psychiatry. 68(4):546-57. PMID: 17474810

6. Lencz T, Smith CW, McLaughlin D, Auther A, Nakayama E, Hovey L, Cornblatt, BA. (2006) Generalized and specific neurocognitive deficits in “prodromal” schizophrenia. Biological Psychiatry, 59(9):863-71. Epub 2005 Dec 1. PMID: 16325151

7. Lencz T, Robinson DG, Xu K, Ekholm J, Sevy S, Gunduz-Bruce H, Woerner MG, Kane JM, Goldman D, Malhotra AK. DRD2 Promoter Region Variation Predicts Sustained Response to Antipsychotic Medication in First Episode Schizophrenia. American Journal of Psychiatry, 2006 Mar;163(3):529-31. PMID: 16513877

8. Lencz T, Smith CW, Auther A, Correll, CU, Cornblatt, B. (2004) Non-specific and attenuated negative symptoms in patients at clinical risk for schizophrenia. Schizophrenia Research, 68(1), 37-48. PMID: 15037338

9. Lencz T, Smith CW, Auther A, Correll CU, Cornblatt, BA. (2003) The assessment of “prodromal schizophrenia”: Unresolved issues and future directions. Schizophrenia Bulletin, 29(4), 717-728. PMID: 14989409

10. Lencz T, Bilder RM, Turkel E, Goldman RS, Robinson D, Kane JM, Lieberman JA. (2003) Impairments in both perceptual competency and maintenence on a visual delayed match-to-sample test in first-episode schizophrenia. Archives of General Psychiatry, 60, 238-43. PMID: 12622656

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