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Researcher Profile - Chris Carter |
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| First Name: | Chris | | Last Name: | Carter | | Title: | Dr | | Advanced Degrees: | B.Sc, M.Sc, Ph.D | | Affiliation: | PolygenicPathways | | Street Address 1: | Flat 2 | | Street Address 2: | 40 Baldslow Rd | | City: | Hastings | | State/Province: | East Sussex | | Zip/Postal Code: | TN34 2EY | Country/Territory: | United Kingdom | | Email Address: |  |
Disclosure:
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Member reports no financial or other potential conflicts of interest. [Last Modified: 2 November 2012]
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View all comments by Chris Carter
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Depression, Bipolar disorder , Schizophrenia, Attention-deficit hyperactivity disorder (ADHD, ADD) , Autism spectrum disorders (pervasive developmental disorders)
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Immunology, Bioinformatics/Statistics, Signal transduction, Epidemiology, Neurotransmission, Pharmacology, Glia/myelin, Genetics, Glutamatergic transmission, Neuroanatomy/Systems Neuroscience
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B.Sc Zoology (Leeds University)
M.Sc with Brenda Costall and Robert Naylor at Bradford University.
Ph.D with Chris Pycock At Bristol University. Dopamine in the frontal cortex and dopamine/serotonin interactions
Postdoc at David Marsden's Neurology department at the Institute of Psychiatry.
Gluatamate pathways and post-mortem studies in Huntington's disease.
Pharmaceutical: Synthelabo/Sanofi-Synthelabo (until 2005)
NMDA antagonists (Ifenprodil)/polyamines
Free radical scavengers
Neuroleptics (Amisulpiride)
Cytotoxic mechanisms in ischaemia
Head of Neuroscience Genomics unit.
Currently: Trawling genes and risk factors.
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Carter C.J. The Fox and the Rabbits—Environmental Variables and Population Genetics (1) Replication Problems in Association Studies and the Untapped Power of GWAS (2) Vitamin A Deficiency, Herpes Simplex Reactivation and Other Causes of Alzheimer's Disease ISRN Neurology 2011 http://www.hindawi.com/isrn/neurology/2011/394678/
Carter C.J. Schizophrenia: A Pathogenetic Autoimmune Disease Caused by Viruses and Pathogens and Dependent on Genes> J Pathogens, 2011
http://www.hindawi.com/journals/jpath/2011/128318/
Carter, C.J. Alzheimer's Disease: A Pathogenetic Autoimmune Disorder Caused by Herpes Simplex in a Gene-Dependent Manner Int.J.Alz.Dis. 2010
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018626/
Carter CJ. Epstein-Barr and other viral mimicry of autoantigens, myelin and
vitamin D-related proteins and of EIF2B, the cause of vanishing white matter
disease: massive mimicry of multiple sclerosis relevant proteins by the
Synechococcus phage. Immunopharmacol Immunotoxicol. 2011 Apr 12. [Epub ahead of
print] PubMed PMID: 21486137.
Carter, C.J. Schizophrenia susceptibility genes directly implicated in the life cycles of
pathogens: cytomegalovirus, influenza, herpes simplex, rubella, and Toxoplasma
gondii. Schizophr Bull. 2009 Nov;35(6):1163-82. PMID: 18552348
Carter, C.J.
eIF2B and oligodendrocyte survival: where nature and nurture meet in bipolar disorder and schizophrenia? Schizophr Bull. 2007 Nov;33(6):1343-53 PMID: 17329232
Carter, C.J.Schizophrenia susceptibility genes converge on interlinked pathways related to glutamatergic transmission and long-term potentiation, oxidative stress and oligodendrocyte viability.
Schizophr Res. 2006 Sep;86(1-3):1-14 [Epub ahead of print] PMID: 16842972
Pycock CJ, Kerwin RW, Carter CJ. Effect of lesion of cortical dopamine terminals on subcortical dopamine receptors in rats. Nature. 1980 Jul 3;286(5768):74-6. PMID: 7393327
Carter CJ, Pycock CJ. Behavioural and biochemical effects of dopamine and noradrenaline depletion within the medial prefrontal cortex of the rat.
Brain Res. 1980 Jun 16;192(1):163-76. PMID: 7189685
properties. J Pharmacol Exp Ther. 1988 Dec;247(3):1222-32. PMID: 2849669
Gotti B, Duverger D, Bertin J, Carter C, Dupont R, Frost J, Gaudilliere B, MacKenzie ET, Rousseau J, Scatton B, et al. Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. I. Evidence for efficacy in models of focal cerebral ischemia. J Pharmacol Exp Ther. 1988 Dec;247(3):1211-21.
Nankai M, Fage D, Carter C. Striatal NMDA receptor subtypes: the pharmacology of N-methyl-D-aspartate-evoked dopamine, gamma-aminobutyric acid, acetylcholine and spermidine release. Eur J Pharmacol. 1995 Nov 3;286(1):61-70. PMID: 8566152
Aubin N, Curet O, Deffois A, Carter C. Aspirin and salicylate protect against MPTP-induced dopamine depletion in mice. J Neurochem. 1998 Oct;71(4):1635-42. PMID: 9751197
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