The Schizophrenia Research Forum holds online discussions periodically on selected topics. Working with one or more researchers who are experts in the topic, we arrange access to published papers or prepare background text as a basis for reader commentary. Currently, we hold two types of discussions:

Live Discussions are scheduled live chats on important recent trends, controversies, or publications. Each discussion is preceded by a background text and led by one or more experts in the topic being discussed. Topics are announced several weeks ahead and advance commentary is solicited. After the live chat, transcripts of discussions are edited and posted.

All Live Discussions will be held from 12 noon-1 p.m. EST unless noted otherwise. Time Zone Converter

Forum Discussions are sometimes topical discussions—as described above, but without the live chat. We will also hold regular Forum Discussions that are like "journal clubs," featuring a recently published paper from Schizophrenia Bulletin. The journal editors will provide a short introduction to the paper, and we invite readers to comment. Full-text access to the paper is available through SRF.

The views of online discussion participants do not necessarily reflect the opinions of the Schizophrenia Research Forum or its editors.

Upcoming Discussions

Ongoing Discussions

TV Neuroscientist—With Schizophrenia, No Less!—Solves Crimes
If you've seen the show, post a comment with your thoughts. If not, you can catch the show Mondays on TNT (10 p.m., EST) and watch back episodes online.

Previous Discussions

Taking Stock of Glutamate in Schizophrenia
Led by Dan Javitt.
Webinar held 5 February 2013.

Neurotropic Infectious Agents and Cognitive Impairment in Schizophrenia
Led by Vishwajit Nimgaonkar.
Webinar held 13 November 2012.

Approaches to Understanding Auditory Hallucinations
Led by Flavie Waters.
Webinar held 13 September 2012.

The Extended Psychosis Phenotype
Led by Jim van Os.
Webinar held 5 April 2012.

Unmet Therapeutic Indications in Schizophrenia—New Standards Based on Recent Experience
In our Forum Discussion “journal club” series, the editors of Schizophrenia Bulletin provide access to the full text of a recent article.

Cognitive Remediation in Schizophrenia: Ready for Widespread Use?
Led by Angus MacDonald.
Webinar held 15 December 2011.

Impairment in Functional Capacity as an Endophenotype Candidate in Severe Mental Illness
In our Forum Discussion “journal club” series, the editors of Schizophrenia Bulletin provide access to the full text of the article.

Neurexin—From Basic Biology to Cognitive Diseases
Led by Thomas Südhof and Steven Clapcote.
Live discussion held 23 March 2011.
View Transcript of Live Discussion

Schizophrenia and Violence, Case Not Closed
SRF has opened a special forum discussion focusing on violence and the mentally ill.

Anhedonia and Emotional Experience in Schizophrenia: Neural and Behavioral Indicators
In our Forum Discussion “journal club” series, the editors of Biological Psychiatry provide access to the full text of two recent articles.

Antipsychotic Dosing: How Much, But Also How Often?
In our Forum Discussion “journal club” series, the editors of Schizophrenia Bulletin provide access to the full text of a recent article.

Clinical Care and Research in the Early Stages of Schizophrenia
Led by S. Charles Schulz.
Live discussion held 30 July 2010.

Cognition in Mouse Models of Schizophrenia Susceptibility Genes
In our Forum Discussion “journal club” series, the editors of Schizophrenia Bulletin provide access to the full text of a recent article.

Language and Schizophrenia
Led by Debra Titone.
Live discussion held 1 April 2010.
View Transcript of Live Discussion

Functional and Dysfunctional Synaptic Plasticity in Prefrontal Cortex
Send in your comments now! The paper under discussion:
Goto Y, Yang CR, Otani S. Functional and dysfunctional synaptic plasticity in prefrontal cortex: roles in psychiatric disorders. Biol Psychiatry. 2010 Feb 1 ; 67(3):199-207. Abstract

DISC1 Roundtable 2010
Led by Akira Sawa and David Porteous.
Live discussion held 13 January 2010.
View Transcript of Live Discussion

Do We Need Schizoaffective Disorder?
Led by Stephan Heckers and Rajiv Tandon.
Live discussion held 15 December 2009.
View Transcript of Live Discussion

Psychiatric Genocide—Nazi Attempts to Eradicate Schizophrenia
Send in your comments now! The paper under discussion:
Torrey EF, Yolken RH. Psychiatric Genocide: Nazi Attempts to Eradicate Schizophrenia. Schizophr Bull. 2009 Sep 16. Abstract

Hippocampus in Schizophrenia Roundtable
Led by Anthony Grace and Stephan Heckers.
Live discussion held 16 November 2009.
View Transcript of Live Discussion

How Might Dysbindin Affect the Schizophrenic Brain?
In our Forum Discussion “journal club” series, the editors of Neuropsychopharmacology provide access to the full text of a recent article.

Neurocognitive Dysfunction in Schizophrenia and Bipolar Disorder
Send in your comments now! The paper under discussion:
Simonsen C, Sundet K, Vaskinn A, Birkenaes AB, Engh JA, Færden A, Jónsdóttir H, Ringen PA, Opjordsmoen S, Melle I, Friis S, Andreassen OA. Neurocognitive Dysfunction in Bipolar and Schizophrenia Spectrum Disorders Depends on History of Psychosis Rather Than Diagnostic Group. Schizophr Bull. 2009 May 14. Abstract

Is the Risk Syndrome for Psychosis Risky Business?
Led by William T. Carpenter Jr.
Live discussion held 22 July 2009.
View Transcript of Live Discussion

The Role of the Social Environment in Psychiatric Research: Outstanding Challenges and Future Directions
Led by Dana March, James Kirkbride, and Wim Veling.
Live discussion held 17 March 2009.
View Transcript of Live Discussion

Neuregulin 1 Roundtable 2009
Led by Amanda Law and David Talmage.
Live Discussion held 24 February 2009.
View Transcript of Live Discussion

DISC1 Roundtable 2009
Led by Akira Sawa, Nick Brandon, and Ty Cannon.
Live discussion held 13 January 2009.
View Transcript of Live Discussion

Synchronized Neural Oscillations in the Pathophysiology of Schizophrenia
Led by Peter Uhlhaas and Kevin Spencer.
Live discussion held 16 December 2008.
View Transcript of Live Discussion

New Approaches to Cognition in Mental Illness
Led by Fred Sabb, Bob Bilder, and Deanna Barch.
Live discussion held 9 June 2008.
View Transcript of Live Discussion

Disease Progression in Schizophrenia
Send in your comments now! The papers under discussion:
Lawrie SM, McIntosh AM, Hall J, Owens DG, Johnstone EC. Brain structure and function changes during the development of schizophrenia: the evidence from studies of subjects at increased genetic risk.

Wood SJ, Pantelis C, Velakoulis D, Yücel M, Fornito A, McGorry PD. Progressive changes in the development toward schizophrenia: studies in subjects at increased symptomatic risk.

Gene Expression Profiling of Postmortem Human Brain
Led by Akira Sawa and Marquis Vawter.
Live discussion held 9 January 2008
View Transcript of Live Discussion

Truly Better Prognosis in the Developing World?
Send in your comments now! The paper under discussion:
Cohen A, Patel V, Thara R, Gureje O. Free Full Text Questioning an Axiom: Better Prognosis for Schizophrenia in the Developing World? Schizophr Bull. 2007 Sep 28; [Epub ahead of print]

Molecular Targets for Treating Cognitive Dysfunction in Schizophrenia
Send in your comments now! The paper under discussion:
Gray JA, Roth BL. Molecular Targets for Treating Cognitive Dysfunction in Schizophrenia. Schizophr Bull. 2007 Jul 7; [Epub ahead of print]

The New Epidemiology of Schizophrenia
Led by John McGrath.
Live Discussion held 11 April 2007.
View Transcript of Live Discussion

Antibodies to Toxoplasma gondii in Patients with Schizophrenia: A Meta-Analysis
Send in your comments now! The paper under discussion:
Antibodies to Toxoplasma gondii in Patients With Schizophrenia: A Meta-Analysis.

The DISC1 Pathway in Major Mental Illness: Clinical, Genetic and Biological Evidence—Current Status and Future Prospects
Led by David Porteous.
Live discussion held 23 January 2007.
View Transcript of Live Discussion

Addressing Cardiovascular Risk Factors in Schizophrenia Patients
The paper under discussion:
Nasrallah HA, Meyer JM, Goff DC, McEvoy JP, Davis SM, Stroup TS, Lieberman JA. Low rates of treatment for hypertension, dyslipidemia and diabetes in schizophrenia: data from the CATIE schizophrenia trial sample at baseline. Schizophr Res. 2006 Sep;86(1-3):15-22. Epub 2006 Aug 1.

Is Active Psychosis Neurotoxic?
The paper under discussion:
McGlashan TH. Is Active Psychosis Neurotoxic? Schizophr Bull. 2006; 32:609-613.

The Lack of Delay in the “Onset” of Antipsychotic Action: Implications from the Bench to the Bedside
Led by Ofer Agid and Shitij Kapur.
Live discussion held 12 September 2006.
View Transcript of Live Discussion

Is BDNF's Star Fading in the Schizophrenia Research Universe?
The paper under discussion:
Tochigi M, Otowa T, Suga M, Rogers M, Minato T, Yamasue H, Kasai K, Kato N, Sasaki T. No evidence for an association between the BDNF Val66Met polymorphism and schizophrenia or personality traits. Schizophr Res. 2006 Jul 17; [Epub ahead of print]

The NIMH-MATRICS Consensus Statement on Negative Symptoms—Schizophrenia Bulletin
The paper under discussion:
Kirkpatrick B, Fenton WS, Carpenter WT Jr, Marder SR. The NIMH-MATRICS Consensus Statement on Negative Symptoms. Schizophr Bull. 2006 Feb 15; [Epub ahead of print]

New Findings in Psychosis: Breaking Down Diagnostic Barriers
Led by Nick Craddock and Mike Owen.
Live discussion held 15 May 2006.
View Transcript of Live Discussion

Identifying Phenotypes and Endophenotypes in Schizophrenia (Psychosis) Research
Led by Irv Gottesman and Mayada Akil.
Live discussion held 10 January 2006.
View Transcript of Live Discussion