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Morrison AP, Hutton P, Shiers D, Turkington D. Antipsychotics: is it time to introduce patient choice? Br J Psychiatry . 2012 Aug ; 201():83-4. PubMed Abstract

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Comment by:  Nev Jones
Submitted 1 October 2012 Posted 2 October 2012
  I recommend this paper

Morrison and colleagues’ commentary raises a number of points worthy of serious consideration. Essentially, the authors question the reflexive use of antipsychotics as the primary, and sometimes only, ongoing treatment for schizophrenia and psychosis, in light of recent research regarding efficacy, toxicity, and the availability of non-pharmacological alternatives.

If we were to take these issues seriously in the context of research, what might the logical next steps be? The disconnect between long-term outcome studies (e.g., Harding et al., 1987a; Harding et al., 1987b; Harrow et al., 2012), in which a substantial percentage of individuals in functional recovery or remission report no longer taking antipsychotics, and shorter-term efficacy studies (e.g., Emsley et al., 2012; Gaebel et al., 2011), suggesting a generalized global benefit to...  Read more

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