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Research News
PAK Inhibitors Restore Spines in DISC1 Mouse Model
18 April 2014. Experimental cancer drugs called PAK inhibitors can promote dendritic spines in a genetic mouse model of psychiatric disorders...
Neural Progenitor Cells Model Aspects of Schizophrenia
14 April 2014. Neural progenitor cells derived from the skin cells of patients with schizophrenia show abnormal neuronal migration and elevated levels of oxidative stress...
Nature Surveys Areas of Schizophrenia Research
9 April 2014. The journal Nature published a supplement surveying some of the hot topics in schizophrenia research...

Nature Supplement Covers Schizophrenia
Nature takes a look at some of the most discussed topics in schizophrenia research in a supplement published April 3. SRF reporter Michele Solis penned the feature on attempts to head off psychosis early, while the other articles cover a range of basic and applied research areas. In addition, Steve Hyman and Steve Marder take on the question of whether we're headed in the right direction in terms of our research
effort, coming to quite different conclusions. The supplement has open access and contains some interesting video segments, including a visit with artist Sue Morgan, who discusses how she designed the cover based on her own experience with schizophrenia. Image courtesy of Nature Outlook
Forum Discussion: The Future of Imaging Genetics?
There has been much head-scratching about how to follow up leads about individual risk variants in the genomes of people with schizophrenia. Perhaps there will be more to be gleaned from combinations of genetic polymorphisms. Writing in Schizophrenia Bulletin, an international team led by Stefan Ehrlich of Dresden University of Technology in Germany presents data that a polygenic risk score can be associated with prefrontal inefficiency, as measured
by functional magnetic resonance imaging.

In our Forum Discussion "journal club" series, the editors of journals provide access to the full text of a recent article. SRF thanks the Maryland Psychiatric Research Center and Oxford University Press, publishers of Schizophrenia Bulletin, for kindly providing open access to the article for this discussion. Editor Vishwajit Nimgaonkar of the University of Pittsburgh gets us started with a short introduction and some questions, and then it's up to our readers to share their ideas, insights, questions, and reactions. Image courtesy of Schizophrenia Bulletin
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Welcome to the Schizophrenia Research Forum website—a virtual community for science about schizophrenia and related disorders. Our Mission is to help researchers in their quest for causes, improved treatments, and better understanding of schizophrenia. Read more about ways to browse the site.
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Comments - Posted 21 April 2014
Read remarks by Ezra Susser about Pedersen CB et al.
NEWS: One in Three Experiences Mental Disorders In Denmark
Jobs - Posted 18 April 2014
Research Assistant/Associat: University of Glasgow, College of Medical, Veterinary and Life Sciences Research Institute of Neuroscience and Psychology, Glasgow, UK.
Conferences - Posted 17 April 2014
Schizophrenia Center 3rd Annual Symposium: 11 June 2014, Thomas B. Turner Building, The Johns Hopkins University School of Medicine, Baltimore, MD, U.S.A.
Comments - Posted 16 April 2014
Read remarks by Albert H. C. Wong about Hayashi-Takagi A et al.
PAPER: PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence.
Grants - Posted 11 April 2014
Novel Tools for Investigating Brain-derived GPCRs in Mental Health Research (R41/R42, R43/R44)

Grants - Posted 11 April 2014
NIH Blueprint Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (R25)
April 21, 2014
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